Journal of Functional Biomaterials.
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Optisol gs fdating 6, Issue 4. No citations found yet 0. Create a SciFeed alert for new publications With following keywords conjunctiva.
By following authors Jon Roger Eidet. One email with all search results. One email for each search. The black arrowhead in the HE photomicrograph indicates mucin granules of goblet cells. The black dotted line indicates the basal membrane, which overlies loose vascularized conjunctival forniceal connective tissue.
Original magnification of the HE photomicrograph: Immunofluorescence photomicrographs of forniceal conjunctival sections show conjunctival epithelial cell which include the goblet cell markers anti-cytokeratin 7 Ck7Ulex europaeus agglutinin 1 UEA-1 lectin and anti-mucin 5AC MUC5ACas well as the marker for stratified squamous non-goblet Optisol gs fdating anti-cytokeratin 4 Ck4.
Nuclei were stained with DAPI blue. Ck4 is only detected in squamous cells between goblet cell clusters.
The basal membrane is indicated Optisol gs fdating the white dotted line. The conjunctival epithelium plays an important role in ensuring the optical clarity of the cornea by providing lubrication to maintain a smooth, refractive Optisol gs fdating, by producing mucins critical for Optisol gs fdating film stability and by protecting against mechanical stress and infectious agents.
A large number of disorders can lead Optisol gs fdating scarring of the Optisol gs fdating through chronic conjunctival inflammation. For controlling complications of conjunctival scarring, surgery can be considered. Surgical treatment of symblepharon
Optisol gs fdating removal of the scar tissue to Optisol gs fdating the deep fornix. The defect is then covered by the application of a tissue substitute.
One obvious limiting factor when using autografts is the size of the defect to be covered, as the amount of healthy conjunctiva is scarce. These limitations have led scientists to develop tissue engineered conjunctival equivalents.
A tissue engineered conjunctival
Optisol gs fdating equivalent needs to be easily manipulated surgically, not cause an inflammatory reaction and be biocompatible. This review summarizes
Optisol gs fdating various substrates and membranes that have been used to culture conjunctival epithelial cells during the last three decades.
Future avenues for developing tissue engineered conjunctiva are discussed. This is an
Optisol Optisol gs fdating fdating access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited CC BY 4.